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Demetrios G Vavvas Selected Research

Receptor-Interacting Protein Serine-Threonine Kinases

9/2012Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration.
6/2011RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death.
12/2010Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis.

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Demetrios G Vavvas Research Topics

Disease

22Macular Degeneration (Age-Related Maculopathy)
04/2022 - 01/2011
15Retinal Detachment (Retinal Detachments)
09/2021 - 12/2010
6Atrophy
10/2021 - 05/2012
6Neoplasms (Cancer)
01/2021 - 01/2013
5Inflammation (Inflammations)
01/2020 - 08/2011
5Necrosis
01/2019 - 12/2010
4Diabetic Retinopathy (Retinopathy, Diabetic)
06/2022 - 01/2016
4Eye Diseases (Eye Disease)
01/2022 - 01/2016
4Retinoblastoma (Glioblastoma, Retinal)
12/2014 - 08/2010
3Retinal Degeneration
01/2022 - 09/2012
3Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 01/2017
3Uveal melanoma
01/2021 - 04/2014
3Wounds and Injuries (Trauma)
01/2020 - 04/2014
3Burns
01/2020 - 04/2014
3Glaucoma
02/2018 - 01/2012
2Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2016
2Blindness (Hysterical Blindness)
01/2022 - 01/2014
2Retinopathy of Prematurity (Retrolental Fibroplasia)
12/2021 - 03/2013
2Geographic Atrophy
06/2021 - 06/2021
2Retinal Diseases
01/2021 - 09/2012
2Melanoma (Melanoma, Malignant)
01/2021 - 10/2019
2Infections
01/2021 - 01/2018
2Retinitis
10/2020 - 09/2012
2Choroidal Neovascularization
11/2019 - 07/2012
2Pathologic Neovascularization
11/2019 - 01/2014
2Corneal Neovascularization
11/2019 - 07/2012
2Epiretinal Membrane (Epiretinal Membranes)
01/2019 - 01/2014
2Atherosclerosis
03/2016 - 01/2016
2Retinal Perforations
07/2014 - 01/2014
2Retinitis Pigmentosa (Pigmentary Retinopathy)
09/2012 - 06/2011
2Uveitis
06/2012 - 08/2011
1Retinal Vein Occlusion
04/2022
1Alzheimer Disease (Alzheimer's Disease)
01/2022
1Dyslipidemias (Dyslipidemia)
01/2022
1Myopia
08/2021
1Vision Disorders (Hemeralopia)
03/2021
1Edema (Dropsy)
01/2021
1Neoplasm Metastasis (Metastasis)
01/2021
1COVID-19
01/2021
1Vasculitis (Vasculitides)
10/2020
1Pain (Aches)
10/2020
1Intervertebral Disc Displacement (Herniated Disc)
10/2020
1Corneal Endothelial Cell Loss
01/2020
1Central Nervous System Diseases (CNS Diseases)
01/2020
1Lymphoma (Lymphomas)
01/2020
1Endophthalmitis (Ophthalmia)
01/2020
1Corneal Injuries
01/2020
1Cicatrix (Scar)
01/2020

Drug/Important Bio-Agent (IBA)

21Retinaldehyde (Retinal)IBA
01/2022 - 12/2010
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2020 - 07/2012
7Phosphotransferases (Kinase)IBA
11/2019 - 08/2010
5Proteins (Proteins, Gene)FDA Link
11/2019 - 01/2011
5AICA ribonucleotide (ZMP)IBA
04/2014 - 08/2010
4Verteporfin (Visudyne)FDA Link
01/2021 - 07/2014
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 01/2012
4AlkaliesIBA
01/2020 - 04/2014
3Biomarkers (Surrogate Marker)IBA
06/2022 - 01/2019
3Complement System Proteins (Complement)IBA
04/2022 - 01/2020
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022 - 03/2016
3LipidsIBA
01/2022 - 01/2016
3Pharmaceutical PreparationsIBA
10/2019 - 01/2013
3CytokinesIBA
02/2018 - 04/2014
3Hyaluronic Acid (Hyaluronan)IBA
05/2014 - 01/2011
3Adenosine Monophosphate (AMP)IBA
04/2014 - 08/2010
3Receptor-Interacting Protein Serine-Threonine KinasesIBA
09/2012 - 12/2010
3CaspasesIBA
06/2011 - 12/2010
2afliberceptIBA
12/2021 - 07/2013
2Fluorescein (Funduscein)FDA LinkGeneric
01/2021 - 10/2020
2necrostatin-1IBA
11/2019 - 07/2014
2Indicators and Reagents (Reagents)IBA
10/2019 - 11/2018
2InflammasomesIBA
01/2019 - 11/2018
2AntioxidantsIBA
01/2018 - 01/2017
2CyclinsIBA
04/2014 - 01/2013
2Protein Kinases (Protein Kinase)IBA
11/2013 - 12/2010
1Apolipoprotein E4IBA
01/2022
1Carnitine (L-Carnitine)FDA LinkGeneric
01/2022
1Thioctic Acid (Lipoic Acid)IBA
01/2022
1Protein Isoforms (Isoforms)IBA
01/2022
1ProdrugsIBA
01/2022
1Complement Inactivating AgentsIBA
06/2021
1Amino AcidsFDA Link
03/2021
1Fatty Acids (Saturated Fatty Acids)IBA
03/2021
1Glycerophospholipids (Phosphoglycerides)IBA
03/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1Heme (Haem)IBA
01/2021
1Messenger RNA (mRNA)IBA
01/2021
1Neuroprotective AgentsIBA
12/2020
1Nicotinamide MononucleotideIBA
12/2020
1NAD (NADH)IBA
12/2020
1CollagenIBA
10/2020
1Complement C3 (C3 Complement)IBA
01/2020
1salicylhydroxamic acid (SHAM)IBA
01/2020

Therapy/Procedure

8Therapeutics
06/2021 - 01/2014
4Vitrectomy
09/2021 - 01/2014
2Lasers (Laser)
11/2019 - 07/2012
2Intraperitoneal Injections
11/2016 - 01/2013
2Vitreoretinal Surgery
09/2014 - 01/2014
1Intravitreal Injections
04/2022
1Drug Therapy (Chemotherapy)
01/2020
1Injections
01/2020